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br p However analyses verified the previously
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(−0.046 ± .042, p = .274). However, analyses verified the previously observed effects of the MAPs intervention on reducing expression of the 19-gene pro-inflammatory subcomponent of the CTRA score (mean changen = −.084 log2 mRNA expression units ± 0.030 SE, p = .013; Bower et al., 2015). Consisten
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br The present data showed that
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The present data showed that CCR4 was highly ex-pressed in some patients with pN0 oral tongue cancer. CCR4 Biotin-tyramide exhibited undetectable to overex-pression levels in oral cancer tissues, and its expres-sion level in human primary tongue tumor tissues was considerably higher than that in
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br differentiated adenocarcinoma case year old man poorly di
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272 differentiated adenocarcinoma; case 2: 51-year-old man, poorly differentiated adenocarcinoma; and case 3: 35-year-old man, 273 poorly differentiated adenocarcinoma. Cases 4 and 5 were a 75-year-old man and a 71-year-old man, respectively, who were 274 H pylori–positive and had well-differe
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2,3-Diaminonaphthalene br Conclusion br Molecular predictors
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5. Conclusion Molecular predictors of recurrence in head and neck/ oral cancer are essential for accurate prognostication; given the recent evidences that affirm the drug resistant and tumorigenic properties of cancer stem cells, investigating the utility of markers specifying them is a signifi
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br Fig Comparison of our
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Fig. 5. Comparison of our proposed model (nsNMF + SVM) with the state-of-the-art methods. Table 2 Biological processes most associated with each cancer type. GO term Cancer Microtubule-based process BRCA Axon guidance GBM Morphogenesis of a polarized epithelium PRAD Chemical syn
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br Global Correlation and Overlaps of Protein and Transcript
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Global Correlation and Overlaps of Protein and Transcript Level Expression Abundance of our three key MDMB-CHMCZCA M3 INPP4B, CDK1, and ERBB2 across tumors of different ER status, tumor grade, and HER2 status correlated well with their respective transcript levels. However, when looking at all
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br Statistical analysis br Data was exported from FACSDiva s
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2.7. Statistical analysis Data was exported from FACSDiva software and managed in Microsoft Excel. The index of platelet activation (IPA) was calculated such that: IPA = gMFI(CD62P) X n(CD41a+CD62P+ events) for each interval, and combined intervals (Fig. 1) [10,36]. IPA allows for de-scription
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br As the catalytic subunit of the telomerase holoenzyme
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As the catalytic subunit of the telomerase holoenzyme complex, human telomerase reverse transcriptase (hTERT), uses its own RNA as template to synthesize telomeres, and then add telomeres to the ends of chromosomes to extend the shortened telomeres and to protect chro-mosomes [18,19]. Therefore, h
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br C M Kopruszinski et
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C.M. Kopruszinski et al. 2009; Pickering et al., 2007, 2008; Smith, Haymond, Smith, & Sweitzer, 2014). In addition, preclinical studies using different cancer models reported elevated endothelin levels in animals that demonstrate evoked hypersensitivity or signs of spontaneous nociception, highl
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br Fig TEM images of biosynthesized SeNPs A B
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Fig. 3. TEM images of biosynthesized SeNPs (A,B) and corresponding SAED pattern (C). Fig. 4. EDS pattern of synthesized selenium nanoparticles. Fig. 5. MTT cytotoxicity analysis: (A) In vitro cell viability of A549 cancer cells upon treated with SeNPs with and without X-ray irradiation; (B)
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br Time lapse recording of
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2.6. Time lapse recording of the spheroid forming process Cells were stained with the fluorescence kits as mentioned. The formation of spheroids was tracked by a time-lapse recording system (Real Time Cell Culture Monitoring (CCM) System, Astec) operated in the fluorescence mode. Cells were ima
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br Screening the chemical library of NPDepo br To
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3.2. Screening the chemical library of NPDepo To discover inhibitors of cancer-specific metabolism, we have used the phenotypic screening system described above to assay 559 com-pounds in the chemical library of NPDepo, and obtained two candidate chemotypes; neoantimycin class of compounds (
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br Malecka Massalska T Smolen A Zubrzycki
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[21] Malecka-Massalska T, Smolen A, Zubrzycki J, Lupa-Zatwarnicka K, Morshed K. Bioimpedance vector pattern in head and neck squamous cell carcinoma. J Physiol Pharmacol 2012;63(1):101e4. [22] Nwosu AC, Mayland CR, Mason S, Cox TF, Varro A, Ellershaw J. The association of hydration status with
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br Next we evaluated the
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Next we evaluated the effects of bimetallic Titanocref (2), Tita-nofin (4) and monometallic Au Auranofin on 3847-29-8 arrest. Titanocref (2) and Titanofin (4) decreased G1/G0 by 32% and 33% respectively and increased the G2/M population by 38% and 36% respectively - compared to DMSO control. Aur
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br PHGDH microscale thermophoresis MST
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PHGDH, microscale thermophoresis (MST) method which had pre-viously been used to investigate protein-protein, small organic mole-cule-protein and antibody-protein interactions was performed. Measuring the thermophoretic behavior of a protein in the presence of different ligand concentrations by MS