• br Auffenberg GB Lane BR Linsell S Cher ML Miller

  2022-09-17

  

  21. Auffenberg GB, Lane BR, Linsell S, Cher ML, Miller DC. Practice-vs physician-level variation in use of active surveillance for men with low-risk prostate cancer: implications for collaborative quality improvement. JAMA surgery. 2017;152(10):978–980. 22. Loeb S, Curnyn C, Fagerlin A, et al. Qu

• br Clinical reports of PBT for unresectable LAPC patients are

  2022-09-17

  

  Clinical reports of PBT for unresectable LAPC patients are extre-mely scarce but clinical outcomes are satisfactory among CCRT reports to this point. To the best of our knowledge, this is the first study to prove the effectiveness of CCRT using Coelenterazine beams by clarifying that high dose ad

• von Minckwitz G et al Clinical

  2022-09-17

  

  von Minckwitz, G., et al., 2008. Clinical response after two cycles compared to HER2, Ki-67, p53, and bcl-2 in independently predicting a pathological complete response after preoperative chemotherapy in patients with operable carcinoma of the breast. Breast Cancer Res. 10, R30. Wapinski, O., Chang

• br Total RNA extraction from plasma br

  2022-09-14

  

  2.2. Total RNA extraction from plasma Whole blood samples were collected from participants after an overnight fasting in EDTA-containing tubes. RNA was extracted from plasma using the miRNeasy Serum/Plasma Kit (Qiagen, Valencia, CA, USA) as per the manufacturer's instructions. RNA spike-in (syn

• br We investigated the impact of NF B activation on

  2022-09-14

  

  We investigated the impact of NF-κB activation on epithelial–me-senchymal transition and angiogenesis in CRC because they are im-portant for tumor proliferation and progression. In the present study, we evaluated epithelial–mesenchymal transition through the im-munohistochemistry of SNAIL and E-ca

• br In agreement with existing literature

  2022-09-08

  

  In agreement with existing literature, we found that Chinese, Filipino, and Japanese women indeed had higher incidence of clear cell ovarian cancer. Endometriosis could partly explain this given that it is a strong risk factor for the clear cell histotype [23]. Miyazawa reported the highest hospit

• LY 379268 br Table br List of genes expressed

  2022-09-08

  

  Table 1 List of genes expressed in the MIA PaCa-2-A cells, but not in the MIA PaCa-2-R LY 379268 and whose gene ontology process includes ‘adhesion’. Symbol Expression in MIA PaCa-2-A cells Probe_ID RefSeq_ID GI Gene Ontology process Top 10 genes are listed in order of expression in

• br Corresponding author at National

  2022-09-07

  

  Corresponding author at: National Institute on Deafness and Other Communication Disorders, National Institutes of Health, 10 Center Drive, Room 7N240B, Bethesda, MD 20892, United States. E-mail addresses: [email protected], [email protected] (N.C. Schmitt). Fig. 1. Schema of immunogenic c

• br Results In early stage NSCLC

  2022-09-07

  

  Results: In early-stage NSCLC, the average Imipenem allele frequency (MAF) in pre-op plasma ctDNA was lower than that in tissue DNA (tDNA). The concordant gene variations between pre-op ctDNA and tDNA were difficult to detect. However, we found the tissue- pre-op plasma concordant ctDNA mutation det

• br Regarding the mtDNA integrity which is determined

  2022-09-07

  

  Regarding the mtDNA integrity, which is determined by the ratio of mtDNA230 to mtDNA79, compared with the healthy controls, EOC patients showed lower levels of the mtDNA integrity. Our findings show that there was more abundant mtDNA79 than 1220 Circulating mtDNA as diagnostic and prognostic bi

• br Conclusion Plasma PCGEM may be a potential

  2022-09-07

  

  Conclusion: Plasma PCGEM1 may be a potential novel circulating biomarker for GC diagnosis and prognosis. Abbreviations: GC, gastric cancer; PCGEM1, prostate cancer gene Compound C marker 1 ; qRT-PCR, reverse transcription-polymerase chain reaction Key words: Gastric cancer, long non-coding R

• br Ebrahimi B Tucker SL Li D

  2022-09-07

  

  [22] Ebrahimi B, Tucker SL, Li D, Abbruzzese JL, Kurzrock R. Cytokines in pancreatic carcinoma: correlation with phenotypic characteristics and prognosis. Cancer 2004;101(12):2727e36. [23] Talbert EE, Lewis HL, Farren MR, Ramsey ML, Rajasekera P, Haverick E, Sarna A, Bloomston M, Pawlik TM, Zim

• br Conclusions br In conclusion

  2022-09-07

  

  5. Conclusions In conclusion, our study indicated that circVAPA was significantly up-regulated in CRC patients’ tissues and Navitoclax and associated with unfavorable clinicopathologic features. CircVAPA could serve as a promising non-invasive biomarker for CRC detection. CircVAPA pro-moted

• br Moreover AFC inhibited the ATP

  2022-09-01

  

  Moreover, AFC5261 inhibited the ATP-triggered IL-1β release from LPS-primed human THP1 TAK-242 in nanomolar concentrations, IC50 = 100.9 nM (Fig. 1A and B). AFC5261 displayed high CNS per-meability (brain/plasma ratio: 0.91) after oral administration and a half-life of approximately 1.5 h (data no

• br For DOX encapsulation the

  2022-09-01

  

  For DOX encapsulation, the DOX was added into the TPP solution prior to Ce6-CSNPs formation. The DOX loadings were 20% with respect to the total amount of CS used for nanoparticles preparation. 2.3. Characterization of Ce6-CSNPs The size distribution of Ce6-CSNPs was determined using dynamic

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