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br The presented reconstruction technique is of general use and
2022-06-21
The presented reconstruction technique is of general use and can be applied in the reconstruction of different cell types, and even in other staining technologies. The analysis can be performed in a timely and cost-effective manner. Therefore, the proposed au-tomatic segmentation method offers con
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br Table br Individual Barriers and Facilitators
2022-06-21
3.4. Aur inhibits Zinc protoporphyrin IX progression The experiments described above investigated the antitumor effect of Aur through growth suppression and induction of apoptosis signaling pathways. Given that the inhibition of USP14 arrests cell cycle through regulating key proteins related to
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c Health Disparities Research The University of Texas MD
2022-06-21
c Health Disparities Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Keywords: Mexican Americans CRP Cancer risk C-Reactive protein (CRP) is a well-known inflammatory marker, and elevated CRP levels has been reported to be associated with the risk of v
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br Table br Correlation of PARK promoter hypermethylation with clinical
2022-05-30
Table 6 Correlation of PARK-2 promoter hypermethylation with clinical parameters in colorectal cancer patients. Characteristics Total cases(n) Methylated PARK-2 (%) Unmethylated PARK-2 (%) P value OR (95% CI) Alcohol OR: odds ratio; CI: confidence interval; WD: well differentiated;
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br Fig ART treatment decreased the frequencies
2022-05-23
Fig. 3. ART treatment decreased the frequencies MDSCs and Tregs in the spleens and tumors of 4T1 TB mice. Flow cytometric analysis of MDSCs (CD11b+ Gr-1+) and Tregs (CD4+ CD25+ Foxp3+) in both the spleen and tumor (A and B). P samples. 2.8. RNA isolation and real-time RT-PCR Trizol reagent
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EE Ct Caq br Ct
2022-05-23
EE (%) = Ct Caq × 100 Ct Where, Ct was the total added drug concentration, Caq was the unloaded drug concentration in aqueous phase. To assess the physical stability, the size, PDI and EE of optimum formulation was determined after 8 weeks storage at 2–6 °C by mentioned methods. 2.4. Cell v
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Cell migration br Epithelial mesenchymal transition br Signalling pathway
2022-05-23
Cell migration Epithelial-mesenchymal transition Signalling pathway Objective. Apatinib, a small molecule inhibitor of VEGFR-2 tyrosine kinase, shows strong anti-tumour activity against various tumours. The function of apatinib in ovarian cancer, however, remains unclear. This study was
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br d Department of Pathology West China
2022-05-20
d Department of Pathology, West China Second University Hospital, Sichuan University, Chengdu, 610041, PR China • PEG-PCL-PEG and DOTAP could assembly into nanomicelles. • MP/DPPP could inhibited cancer proliferation in vitro. • MP/DPPP could induced cancer apoptosis in vitro. • MP/DPP
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br Results OHIS was positively associated
2022-05-18
Results: OHIS was positively associated with information overload and health literacy; information overload was negatively associated with health literacy. Health literacy was positively associated with decisional balance; decisional balance was positively associated with uptake of sigmoidoscopy a
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br The first three algorithms
2022-05-18
The first three algorithms have been detailed in Section 1.5 and in [26,27], while the others are discussed below and applied to the SPA-PAL2v computational structure. The general form of how SPA-PAL2v is applied in Lipo3000 cancer di-agnosis is shown in the flowchart of Fig. 3. As can be s
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br Methods Whole exome sequencing MC data from
2022-05-18
Methods. Whole-exome sequencing MC3 data from primary endometrioid and serous carcinomas (n = 232) and uterine carcinosarcomas (n = 57) from The Cancer Genome Atlas (TCGA), and matched primary and metasta-tic ECs (n = 61, 26 patients) were reanalyzed, subjected to mutational signature analysis usi
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br Results br Individual Patient Derived Gastric Cancer Organoids
2022-05-17
Results Individual Patient-Derived Gastric Cancer Organoids Display Unique Responses to Chemotherapeutic Drugs and Targeted Therapy We generated an initial bank of gastric cancer organoids from tumors obtained from 7 patients (Table 1). For each patient from whom the organoids were derived,
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br In light of this significant efforts are
2022-05-15
In light of this, significant efforts are currently devoted for explora-tion of novel, less toxic and effective anti-cancerous agent(s) from me-dicinal plants. Withania somnifera, belonging to the family Solanaceae, is a well-known and widely used plant in Indian traditional medicine system. In mo
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br The amplicon containing ERBB and its flanking
2022-05-13
The amplicon containing ERBB2 and its flanking Y-27632 was co-localized with the amplicon on 8p11 in eight tumors, and with the amplicon on 11q13 in seven tumors, as shown in Table 2. In these tumors (excluding Case 14), the two ampli-cons were observed separately in individual nuclei (Fig. 5E).
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br Statement of Significance br
2022-05-10
Statement of Significance Brain metastasis (BM) of non-small cell lung cancer (NSCLC) is a complex cascade, and in particular, the process of lung cancer cells penetrating the blood–brain barrier (BBB) is very unique. However, due to the lack of reliable models that can faithfully mimic the dyn