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br Polybrominated diphenyl ethers occurrence dietary exposur
2019-09-23
Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology. Environmental Working Group. In the dust. Toxic Fire Retardants in American Homes Washington, D.C.: Environmental Working Group; 2007 [Available from: http:// www.ewg.org/node/8452. Toxicological function of adipos
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br The missing value estimation by BPCM
2019-09-23
2. The missing value estimation by BPCM always outperforms the other two algorithms investigated, which demon-strated the effectiveness of the proposed approach; 3. The proposed approach can achieve a relatively high accuracy and sensitivity in cervical cancer screening. 6. Conclusion Ce
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br Methods br Study design
2019-09-23
Methods Study design This study was approved by the Memorial Sloan Kettering Cancer Center Institutional Review Board. From our multidisciplinary breast cancer database of consecutive 13,042 patients who received definitive surgery for non-metastatic, invasive breast cancer between 1998 a
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br A screening trial Stockholm invited
2019-09-23
A screening trial (Stockholm, 1988–1989) invited 2400 men aged 55–70 yr only once and found no difference in PCa mortality after 20 yr from a nonscreened source population; however, statistical power was limited [21]. Similar results were observed in the present study: men aged 70–74 yr were invi
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br mechanistical studies br To
2019-09-23
mechanistical studies. To further examine the effects of 8-AHN on cell proliferation and survival, HCT116 cells were treated with 5 μM 8-AHN at 0, 24, 48 h. FCM showed that the percentage of cells at the G2/M phase sig-nificantly increased from 29.2% to 53.1% or 57.9% after treatment with 5 μ
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br Keywords FU Arrhythmias Colon cancer Ischemia Rectal
2019-09-16
Keywords: 5FU, Arrhythmias, Colon cancer, Ischemia, Rectal cancer Introduction 5-Fluorouracil (5-FU) represents the backbone of systemic therapy regimens of colorectal cancer (CRC), both in the adjuvant and metastatic settings.1 In addition to the common toxicities of 5-FU (like diarrhea and
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T-5224 br In recent years Chinese medicine has emerged as
2019-09-16
In recent years, Chinese medicine has emerged as an attractive source for a new generation of autophagy inhibitors (Fu et al., 2018; Song et al., 2017). Ginsenoside Rg3, an active ingredient of Panax ginseng, exerts anticancer effects on some cancers (Lee et al., 2015; Wu et al., 2015). Ginsenoside
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Accepted Manuscript br A year period analysis of other
2019-09-16
Accepted Manuscript A 25-year Cefepime analysis of other-cause mortality in localized prostate cancer Sophie Knipper, Angela Pecoraro, Carlotta Palumbo, Giuseppe Rosiello, Stefano Luzzago, Zhe Tian, Alberto Briganti, Fred Saad, Derya Tilki, Markus Graefen, Pierre I. Karakiewicz To appear in
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br Patients and methods According
2019-09-02
Patients and methods According to previous clinical experiences, lesions were treated with a dose of 3 x 9 Gy over three consecutive days [10,[17], [18], [19]]. Doses were usually prescribed to the 80% isodose line with a minimum 95% target coverage of the prescribed dose. The planned radiation d
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Identification of somatic EGFR mutations has been integrated
2019-08-26
Identification of somatic EGFR mutations has been integrated with the diagnosis of lung adenocarcinoma in therapeutic protocols [33]. Commercial kits, including the therascreen® EGFR RGQ PCR kit, cobas® EGFR mutation test, and MassARRAY® genotyping, are commonly applied in clinical practice in most
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In multivariate analysis both the cribriform component HR
2019-08-26
In multivariate analysis, both the cribriform component (HR of RFS, 2.82, 95% CI, 1.68–4.74, p ABT-888 (Veliparib) the poor prognostic association with STAS is due to other clinicopathological factors, our study found that STAS remained an independent prognostic predictor for worse outcomes, which w
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br Funding br Disclosure br Author contribution br Acknowled
2019-08-16
Funding Disclosure Author contribution Acknowledgement Introduction The overall incidence of head and neck cancers (HNC) has declined in recent years in high income countries (HIC) [1]. A closer analysis has shown two patterns: an increasing trend for HPV-related HNC that mainly arise
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br Methods Study population Our
2019-08-16
Methods Study population: Our study was based on electronic records from the largest health maintenance organization in Israel, Clalit Health Services, insuring 53% (4.3 million) of the nation's population. All persons 21–89 years old on January 1, 2002 were included in a closed cohort that was f
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Coffee particularly regular brewed coffee
2019-08-16
Coffee, particularly regular brewed coffee, and tea are among commonly consumed beverages in Canada [36]. Despite the existence of biologically plausible evidence suggesting that these beverages, as well as caffeine, may influence a woman’s risk of cancer, very few studies have been conducted to ass
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A role for endogenous hormones in
2019-08-11
A role for endogenous Prostaglandin J2 in the gender discrepancy in liver cancer risk has been hypothesized, with most speculation focusing on testosterone or estradiol [[5], [6], [7], [8]]. However, the role of estrogenic exposures remains unclear, as studies have reported mixed results for parity
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